Just installed wordpress 2.5 on one of my blog to upgrade the RC2 version. Looks good on the admin side, I have seen some feed issue on rc1 and rc2 on IE6 where the feed in not loading correctly. It might be a theme issue or wordpress 2.5 itself. I cannot verify this latest version since i am not using anymore IE6. I have accessed only my site on some netcafe that have IE6 installed.

Here some news on Wordpress 2.5. Dougal Gunters blog.

First of all, in my post about Release Candidate 1, I mentioned that I had problems with the plugin updater. Since that time, I have been able to upgrade complex plugins with out a problem. I didn’t do extensive testing, but I feel like this is probably safer now. Other folks on the wp-testers mailing list have reported observed improvements similar to mine.

on wordpress development blog

WordPress 2.5, the culmination of six months of work by the WordPress community, people just like you. The improvements in 2.5 are numerous, and almost entirely a result of your feedback: multi-file uploading, one-click plugin upgrades, built-in galleries, customizable dashboard, salted passwords and cookie encryption, media library, a WYSIWYG that doesn’t mess with your code, concurrent post editing protection, full-screen writing, and search that covers posts and pages.